ENCYCLOPEDIA DETAIL

DISEASE

Basal Laminar Drusen

Retina
Basal laminar drusen are small, round, uniformly sized, yellow drusen (accumulations of extracellular material that build up in the eye) scattered in clusters between the pigment epithelial layer and the bottom-most Bruch’s membrane of the retina. Imaging technologies such as fluorescein angiography (FA) depict basal laminar drusen as appearing in a “starry sky” pattern.
Basal laminar drusen often are seen in conjunction with a pseudovitelliform detachment of the macula. Alone, these kind of drusen have little or no effect on vision.
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